LIFS researchers reveal mechanism governing AMPAR synaptic targeting and clustering

Prof. Mingjie Zhang and his team reported that stargazin uses its entire C-terminal tail bind PSD-95 via a specific and multivalent interaction mode. Their findings, published in Neuron, reveal the mechanism of AMPA receptor synaptic trafficking and transmission at the neuronal synapses. Read More

An iPSC model reveals the underlying mechanism of transcriptional and synaptic dysregulation in mental disorders

Prof. Mingjie Zhang and his collaborators Prof. Ming from the University of Pennsylvania reported a DISC1 and ATF4 interaction in iPSC-derived neurons with a DISC1 mutation. Their findings, published in Molecular Psychiatry, reveal the underlying mechanisms linking the genetic lesion and functional phenotypes of psychiatric disorders. Read More

The First Alumni Reunion of LIFS

The First Alumni Reunion was held successfully on May 18, 2019, by the Division of Life Science and Life Science Alumni Association, HKUST Read More

New insights into membrane trafficking regulated by ER fusion protein

Prof. Yusong Guo and his collaborators reported that the endoplasmic reticulum fusogen atlastin was involved in regulating cargo mobility and COPII formation in the ER. Their finding, published in PNAS on June 25, provides important insight into the physiological role of the tubular ER network. Read More

Metaphocytes, a new cell type involving in immune in zebrafish

Dr. Zilong Wen’s laboratory has recently identified a myeloid-like cell population in zebrafish epidermis. This newly identified myeloid-like cell population, designated as metaphocytes, are of ectodermal origin but shares high similarities with mesoderm-derived conventional macrophages in the skin. Read More

Prof. Jiguang Wang received the “School of Engineering Young Investigator (Rising Star) Research Award 2018/19

Congratulations to Prof. Jiguang Wang on winning the “School of Engineering Young Investigator (Rising Star) Research Award 2018/19. He received the award plaque and cash prize from the Dean of Engineering Prof Tim Cheng in the School Board meeting on 26 April, 2019. Read More

EpiHK 2019 Spring Symposium

The EpiHK 2019 Spring Symposium took place at HKUST on Febuary 20, 2019, bringing together the research community working on epigenomics for the first EpiHK research symposium. Read More

Vps4 protein helps delay degradation of injured nerves

A research team consisting of scientists from the HKUST, the Chinese Academy of Sciences, and Jinan University discovered a new mechanism that could delay the degeneration of injured nerves, bringing new hope to the treatment of nerve damage and neurodegenerative diseases such as Parkinson and Amyotrophic Lateral Sclerosis (ALS). Read More