Research Question

My goals are to help bridge gaps between biology and engineering. To do so, my group’s research focus has two major directions:
1) investigating disease mechanisms using novel approaches such as single cell transcriptomics and gene editing;
2) development of new technologies and tools to address experimental challenges in life science research.

Representative Publications

1. Wu AR, Wang J, Streets AM, Huang Y. 2017. Single-Cell Transcriptional Analysis. Annu Rev Anal Chem. 10(1):439–62
2. Treutlein B, Brownfield DG, Wu AR, Neff NF, Mantalas GL, et al. 2014. Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature. 509(7500):371–75
3. Wu AR, Neff NF, kalisky T, Dalerba P, Treutlein B, et al. 2014. Quantitative assessment of single-cell RNA-sequencing methods. Nature Methods. 11(1):41–46
4. Wu AR, Kawahara TLA, Rapicavoli NA, van Riggelen J, Shroff EH, et al. 2012. High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation. Lab on a chip. 12(12):2190–98
5. Wu AR, Hiatt JB, Lu R, Attema JL, Lobo NA, et al. 2009. Automated microfluidic chromatin immunoprecipitation from 2,000 cells. Lab on a chip. 9(10):1365–70

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