Prof. Mingjie Zhang and his team reported that stargazin uses its entire C-terminal tail bind PSD-95 via a specific and multivalent interaction mode. Their findings, published in Neuron, reveal the mechanism of AMPA receptor synaptic trafficking and transmission at the neuronal synapses.
Prof. Mingjie Zhang and his collaborators Prof. Ming from the University of Pennsylvania reported a DISC1 and ATF4 interaction in iPSC-derived neurons with a DISC1 mutation. Their findings, published in Molecular Psychiatry, reveal the underlying mechanisms linking the genetic lesion and functional phenotypes of psychiatric disorders.
Prof. Yusong Guo and his collaborators reported that the endoplasmic reticulum fusogen atlastin was involved in regulating cargo mobility and COPII formation in the ER. Their finding, published in PNAS on June 25, provides important insight into the physiological role of the tubular ER network.
Prof. Mingjie Zhang has just won a highly competitive three-year grant from the Human Frontiers in Science Program (HFSP) to investigate the molecular mechanism by which calcium ion determines AMPA receptor trafficking and retention at the neuronal synapse.
Dr. Zilong Wen’s laboratory has recently identified a myeloid-like cell population in zebrafish epidermis. This newly identified myeloid-like cell population, designated as metaphocytes, are of ectodermal origin but shares high similarities with mesoderm-derived conventional macrophages in the skin.
Congratulations to Prof. Jiguang Wang on winning the “School of Engineering Young Investigator (Rising Star) Research Award 2018/19. He received the award plaque and cash prize from the Dean of Engineering Prof Tim Cheng in the School Board meeting on 26 April, 2019.