Using zebrafish as an animal model, Prof. Zilong Wen and his research team identified two distinct microglial populations – the phagocytotic microglia and regulatory microglia. Their findings were published in the journal Science Advances.
Dr. Zilong Wen’s laboratory has recently identified a myeloid-like cell population in zebrafish epidermis. This newly identified myeloid-like cell population, designated as metaphocytes, are of ectodermal origin but shares high similarities with mesoderm-derived conventional macrophages in the skin.