Zhenguo WU

Professor

PhD University of Western Ontario

bczgwu@ust.hk

23588704

Molecular regulation of muscle stem cells, myogenic differentiation, and muscle regeneration.

Diao, Y., Guo, X., Li, Y., Sun, K., Lu, L., Jiang, L., Fu, X., Zhu, H., Sun, H., Wang, H., and Wu, Z. (2012) Pax3/7BP Is a Pax7- and Pax3-Binding Protein that Regulates the Proliferation of Muscle Precursor Cells by an Epigenetic Mechanism. Cell Stem Cell 11:231-41.
Zhu H, Xiao F, Wang G, Wei X, Jiang L, Chen Y, Zhu L, Wang HX, Diao Y, Wang HT, Ip NY, Cheung TH, and Wu Z (2016). STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration. Cell Rep 16: 2102-15.
An Y, Wang G, Diao Y, Long Y, Fu X, Weng M, Zhou L, Sun K, Cheung TH, Ip NY, Sun H, Wang HT, and Wu Z (2017). A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes. Dev Cell. 41: 382-91.
Wang G, Zhu H, Situ C, Han L, Yu Y, Cheung TH, Liu K, and Wu Z (2018). p110α of PI3K is necessary and sufficient for quiescence exit in adult muscle satellite cells. EMBO J. e98239. (published online 26.03.2018)
Zhou S, Han L, Weng M, Zhu H, Heng Y, Wang G, Shen Z, Chen X, Fu X, Zhang M, and Wu Z (2021). Paxbp1 controls a key checkpoint for cell growth and survival during early activation of quiescent muscle satellite cells. Proc Natl Acad Sci U S A. 118: e2021093118.