Research Question

The Ishibashi laboratory is interested in studying transcription elongation dynamics and the functional roles of nucleosomes on transcription regulation

Representative Publications

1. Ishibashi T*, Dangkulwanich M*, Coello Y*, Lionberger TA, Lubkowska L, Ponticelli AS, Kashlev M, Bustamante C. (2014) Complete dissection of transcription elongation reveals slow translocation of Pol II in a linear ratchet mechanism, Proc. Natl. Acad. Sci. USA, 111(9), 3419-24.
2. Dangkulwanich M, Ishibashi T, Bintu L, Bustamante C. (2014) Molecular mechanisms of transcription through single-molecule experiments, Chem. Rev., 114(6), 3203-23.
3. Dangkulwanich M*, Ishibashi T*, Liu S*, Kireeva ML, Lubkowska L, Kashlev M, Bustamante C. (2013) Complete dissection of transcription elongation reveals slow translocation of Pol II in a linear ratchet mechanism, Elife, 2, e00971.
4. Bintu L*, Ishibashi T*, Dangkulwanich M, Wu Y, Lubkowska L, Kashlev M, Bustamante C. (2012) Nucleosomal elements that control the topography of the barrier to transcription, Cell, 151(4), 738-49.
5. Ishibashi T.*, Li A.*, Eirín-López J.M., Ming M., Abbott D.W., Meistrich M.L., Ausió J. (2010) H2A.Bbd: An X-chromosome-encoded histone involved in mammalian spermiogenesis, Nucleic Acids Research, 38(6), 1780-9.