Determination of protein sequences and three-dimensional structures; relationship between structure and function; principles of protein design and engineering; molecular, biochemical and genetic approaches to study protein function and regulation.
Fundamental concepts of drug action and toxicity; clinically useful agents in central and peripheral disorders; toxicology of drugs and agents that are hazardous to living organisms.
Recent advances in the study of the molecular mechanisms of cell function, with an emphasis on the structure and function of signaling components that control cell growth, differentiation, and integrated responses in eukaryotic cells.
Fundamentals in the epidemiology, etiology and treatment of cancers; basic mechanisms of carcinogenesis. For LIFS/BIBU students in their fourth year of study.
Cellular, biochemical and genetic basis of immunity; cells in immune response, antigens and antigen recognition; antibodies and the generation of diversity; major histocompatibility complex; cell mediated immune response; regulation of immune response; autoimmunity, tissue transplantation and rejection.
Introduction to the molecular understanding of brain function, building upon the basis of biochemistry and biology. Four specific themes are covered: (i) structural neurochemistry and neural membranes; (ii) synapses, transmitters and receptors; (iii) cellular and (iv) medical and behavioral neurochemistry.
This course covers the clinical manifestations, physiology, pathophysiology and treatment of common human diseases, with focus on the underlying biochemical basis of the diseases and treatment.
Many variations in the human population such as hair thickness, tolerance to milk in adults, high blood cholesterol and susceptibility to certain types of cancer can be determined by genetic factors. This course will cover the principles and up to date technologies for the discovery and analysis of human genetic variation. The application of basic scientific knowledge in a clinical setting will be discussed.
Current status and future potential of Biotechnology, with emphasis on the fundamentals of plant molecular biology and biotechnology. Using examples of marketable products from food industry, Traditional Chinese Medicine (TCM) and agricultural fields. The role of basic research in the development and production biotechnology products will be described.
