Life science is now at an unprecedented stage because of the development of new biotechnologies and the following ground-breaking discoveries in the past decades. This course is dedicated to sharing the latest breakthroughs, how they are discovered, the principles and applications, and pinpointing the opportunities we will embrace. Topics include state-of-the-art technologies such as genome editing techniques, super-resolution microscopies, DNA nanotechnology, omics, and the latest biotechnology approaches to investigate and tackle diseases such as COVID-19, hereditary diseases, and cancers.